Corneobiology refers to experimental studies that are focused on the anatomy and biolology of the stratum corneum, the most superficial layer of the skin. U.S. dermatologist Dr. Albert Kligman and his team found out that the stratum corneum and the lipid barrier, that keeps it intact, play a significant role in skin health. The skin has always had a very crucial meaning. Hippocrates already studied formulas for the elimination of "traces of aging" (1).
What we see on the skin surface is the upper layer, which has a lot of functions:
Corneotherapy refers to the treatment based on corneobiology to reach more effectiveness and safety, using lower concentrations of active agents, with fewer adverse side effects (such as stinging, burning and irritancy), free of fragrances, allergens and preservatives, more agreeable to use, being colour- and odourless (2).
Nowadays, the best-seller product is a hydrating cream. What about serums, are they better? The difference between a cream and a serum lies in the galenic formulation, which deals with the principles of medicines in order to optimize their absorption.