Corneobiology refers to experimental studies that are focused on the anatomy and biolology of the stratum corneum, the most superficial layer of the skin. U.S. dermatologist Dr. Albert Kligman and his team found out that the stratum corneum and the lipid barrier, that keeps it intact, play a significant role in skin health. The skin has always had a very crucial meaning. Hippocrates already studied formulas for the elimination of “traces of aging” (1).
Functions of the top layer of skin
What we see on the skin surface is the upper layer, which has a lot of functions:
Permeability: measure of the ability of a material to transmit fluids
Antimicrobial: property to kill microorganisms or stop their growth
Antioxidant: capacity to stop the production of free radicals, which damage the cells of organisms
Integrity or cohesion: ability for intermolecular attraction between like-molecules
Mechanical/rheological: science of deformation and flow within a material
Chemical/exclusion of antigens: barrier against e.g. virus
Psychosensory: touch affects psychological and emotional health
Hydration: supply and retention of adequate water in biological tissues
Protection against electromagnetic radiation
Initiation of inflammation: activation of cytokines (proteins important in cell signaling)
The concept of corneotherapy
Corneotherapy refers to the treatment based on corneobiology to reach more effectiveness and safety, using lower concentrations of active agents, with fewer adverse side effects (such as stinging, burning and irritancy), free of fragrances, allergens and preservatives, more agreeable to use, being colour- and odourless (2).
Corneotherapy serums
Nowadays, the best-seller product is a hydrating cream. What about serums, are they better? The difference between a cream and a serum lies in the galenic formulation, which deals with the principles of medicines in order to optimize their absorption.
A serum is a low-viscosity gel that allows carrying a high concentration of active ingredients. In addition, the serum provides a lot of moisture and thus absorbs quickly. The cushioning effect of anti-aging serums is therefore immediately visible. However, the serum contains hardly any moisturizing ingredients. Nevertheless, skin care products designed to increase the skin’s moisture content are the most wanted ones.
Moisturizing skin care
The use of moisturizing factors is an essential principle of the moisturizing and rehydrating care of dry skin. Moreover, they are also helpful in the treatment and preventative care of aged skin, as they complement the natural barrier of the skin, protect against dehydration and can smooth fine lines through discrete swelling of the stratum corneum (3). For this reason, a routine based on the application of a serum and then hydration with a cream represents a good combination.
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